Geneva University Neurocenter
Valentina Garibotto

Valentina Garibotto

Function: Professeure associée

Group name: Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTLab)

Group type: Main

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Radiology and Medical Informatics

Domains: Development and Plasticity

Keywords: biomarkers, molecular neuroimaging, neurodegeneration, neurotransmission

Research activities

Our research group works on molecular neuroimaging, a tool allowing the in vivo measurement of protein deposits, brain metabolism and neurotransmission. Molecular imaging has changed the way we understand brain disorders, especially those associated with neurodegeneration. In this field, the current gold standard is still neuropathology at post-mortem: this represents an intrinsic limitation for the development and assessment of targeted therapies. The availability of in vivo biomarkers of the disease, among these molecular imaging, finally offers an opportunity for precision medicine in degenerative disorders and has already changed how we evaluate patients and how we test new drugs. Our group benefits from a unique and privileged position, on one hand working in close collaboration with various research groups at the Geneva University and abroad and on the other hand being embedded in a clinical division of the Geneva University Hospitals for patient diagnosis and care. This position allows us to translate new ideas and knowledge, coming from basic and applied research programs, into procedures that can be tested in clinical studies and validated for clinical practice.

Latest publications

Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex.

Ossenkoppele R , Coomans EM , Apostolova LG , Baker SL , Barthel H , Beach TG , Benzinger TLS , Betthauser T , Bischof GN , Bottlaender M , Bourgeat P , den Braber A , Brendel M , Brickman AM , Cash DM , Carrillo MC , Coath W , Christian BT , Dickerson BC , Dore V , Drzezga A , Feizpour A , van der Flier WM , Franzmeier N , Frisoni GB , Garibotto V , van de Giessen E , Domingo-Gispert J , Gnoerich J , Gu Y , Guan Y , Hanseeuw BJ , Harrison TM , Jack CR , Jaeger E , Jagust WJ , Jansen WJ , La Joie R , Johnson KA , Johnson SC , Kennedy IA , Kim JP , van Laere K , Lagarde J , Lao P , Luchsinger JA , Kern S , Kreisl WC , Malotaux V , Malpetti M , Manly JJ , Mao X , Mattsson-Carlgren N , , Messerschmidt K , Minguillon C , Mormino EM , O'Brien JT , Palmqvist S , Peretti DE , Petersen RC , Pijnenburg YAL , Pontecorvo MJ , Poirier J , , Rabinovici GD , Rahmouni N , Risacher SL , Rosa-Neto P , Rosen H , Rowe CC , Rowe JB , Rullmann M , Salman Y , Sarazin M , Saykin AJ , Schneider JA , Schöll M , Schott JM , Seo SW , Serrano GE , Shcherbinin S , Shekari M , Skoog I , Smith R , Sperling RA , Spruyt L , Stomrud E , Strandberg O , Therriault J , Xie F , Vandenberghe R , Villemagne VL , Villeneuve S , Visser PJ , Vossler H , Young CB , Groot C , Hansson O
Nature neuroscience - Jul 2025

Utility, Costs and Cost-Utility of Amyloid-PET in the Diagnostic Process of Memory Clinic Patients: A Trial-Based Economic Evaluation From AMYPAD-DPMS.

van Maurik IS , Altomare D , Collij LE , Caprioglio C , Moro C , Garibotto V , Demonet JF , Scheltens P , Farrer G , Gismondi R , Stephens AW , Gispert JD , Molinuevo JL , Grau-Rivera O , Edison P , Walker Z , Jessen F , Dzrezga A , Zeyen P , Payoux P , Saint-Aubert L , Delrieu J , Nordberg A , Barkhof F , Frisoni GB , Berkhof J
European journal of neurology - Jun 2025

Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity.

Moscoso A , Heeman F , Raghavan S , Costoya-Sánchez A , van Essen M , Mainta I , Camacho V , Rodríguez-Fonseca O , Silva-Rodríguez J , Perissinotti A , Gu Y , Yun J , Peretti D , Ribaldi F , Coomans EM , Brum WS , Grothe MJ , Aguiar P , Bischof GN , Drzezga A , Seo SW , Villeneuve S , Malpetti M , O'Brien JT , Rowe JB , van de Giessen EM , Ossenkoppele R , Jagust WJ , Smith R , Hansson O , Frisoni GB , Garibotto V , Soleimani-Meigooni DN , Carrillo M , Dickerson BC , La Joie R , Rabinovici GD , Apostolova LG , LaMontagne PJ , Pontecorvo MJ , Johnson KA , Sperling RA , Weiner MW , Petersen RC , Jack CR , Vemuri P , Schöll M ,
JAMA - Jul 2025
See the complete list of the publications

Contact

Département de radiologie et informatique médicale
Faculty of Medicine

Service de Médecine nucléaire et imagerie moléculaire, Département diagnostique
HUG
Email: valentina.garibotto@hcuge.ch