
Valentina Garibotto
Group name: Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTLab)
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Radiology and Medical Informatics
Domains: Development and Plasticity
Keywords: biomarkers, molecular neuroimaging, neurodegeneration, neurotransmission
Research activities
Our research group works on molecular neuroimaging, a tool allowing the in vivo measurement of protein deposits, brain metabolism and neurotransmission. Molecular imaging has changed the way we understand brain disorders, especially those associated with neurodegeneration. In this field, the current gold standard is still neuropathology at post-mortem: this represents an intrinsic limitation for the development and assessment of targeted therapies. The availability of in vivo biomarkers of the disease, among these molecular imaging, finally offers an opportunity for precision medicine in degenerative disorders and has already changed how we evaluate patients and how we test new drugs. Our group benefits from a unique and privileged position, on one hand working in close collaboration with various research groups at the Geneva University and abroad and on the other hand being embedded in a clinical division of the Geneva University Hospitals for patient diagnosis and care. This position allows us to translate new ideas and knowledge, coming from basic and applied research programs, into procedures that can be tested in clinical studies and validated for clinical practice.
Latest publications
Analysis of Psychological Symptoms Following Disclosure of Amyloid-Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline.
Low-dose brain irradiation normalizes TSPO and CLUSTERIN levels and promotes the non-amyloidogenic pathway in pre-symptomatic TgF344-AD rats.
Manual and semi-automated approaches to MIBG myocardial scintigraphy in patients with Parkinson's disease.
The Early Diagnosis of Alzheimer's Disease: A Patient-Centred Conversation with the Care Team.
Videos
Contact
Département de radiologie et informatique médicale
Faculty of Medicine
Service de Médecine nucléaire et imagerie moléculaire, Département diagnostique
HUG
Email: valentina.garibotto@hcuge.ch