Function: Professeure associée
Group name: Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTLab)
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Radiology and Medical Informatics
Domains: Development and Plasticity
Keywords: biomarkers, molecular neuroimaging, neurodegeneration, neurotransmission
Our research group works on molecular neuroimaging, a tool allowing the in vivo measurement of protein deposits, brain metabolism and neurotransmission. Molecular imaging has changed the way we understand brain disorders, especially those associated with neurodegeneration. In this field, the current gold standard is still neuropathology at post-mortem: this represents an intrinsic limitation for the development and assessment of targeted therapies. The availability of in vivo biomarkers of the disease, among these molecular imaging, finally offers an opportunity for precision medicine in degenerative disorders and has already changed how we evaluate patients and how we test new drugs. Our group benefits from a unique and privileged position, on one hand working in close collaboration with various research groups at the Geneva University and abroad and on the other hand being embedded in a clinical division of the Geneva University Hospitals for patient diagnosis and care. This position allows us to translate new ideas and knowledge, coming from basic and applied research programs, into procedures that can be tested in clinical studies and validated for clinical practice.
Patterns of amyloid accumulation in amyloid-negative cases.
Unsupervised [F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer's disease.
Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial.
Plasma biomarkers for Alzheimer's disease: a field-test in a memory clinic.
Département de radiologie et informatique médicale
Faculty of Medicine
Service de Médecine nucléaire et imagerie moléculaire, Département diagnostique