Valentina Garibotto

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Radiology and Medical Informatics

Group name: Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTLab)

Keywords: biomarkers, molecular neuroimaging, neurodegeneration, neurotransmission

Research activities

Our research group works on molecular neuroimaging, a tool allowing the in vivo measurement of protein deposits, brain metabolism and neurotransmission. Molecular imaging has changed the way we understand brain disorders, especially those associated with neurodegeneration. In this field, the current gold standard is still neuropathology at post-mortem: this represents an intrinsic limitation for the development and assessment of targeted therapies. The availability of in vivo biomarkers of the disease, among these molecular imaging, finally offers an opportunity for precision medicine in degenerative disorders and has already changed how we evaluate patients and how we test new drugs. Our group benefits from a unique and privileged position, on one hand working in close collaboration with various research groups at the Geneva University and abroad and on the other hand being embedded in a clinical division of the Geneva University Hospitals for patient diagnosis and care. This position allows us to translate new ideas and knowledge, coming from basic and applied research programs, into procedures that can be tested in clinical studies and validated for clinical practice.

Latest publications

Projection-space implementation of deep learning-guided low-dose brain PET imaging improves performance over implementation in image-space.

Sanaat A , Arabi H , Mainta I , Garibotto V , Zaidi H

Journal of nuclear medicine : official publication, Society of Nuclear Medicine - Jan 2020

Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects.

Haller S , Montandon ML , Rodriguez C , Garibotto V , Herrmann FR , Giannakopoulos P

Neuro-degenerative diseases - Dec 2019

Metabolic correlates of dopaminergic loss in dementia with lewy bodies.

Huber M , Beyer L , Prix C , Schönecker S , Palleis C , Rauchmann BS , Morbelli S , Chincarini A , Bruffaerts R , Vandenberghe R , Van Laere K , Kramberger MG , Trost M , Grmek M , Garibotto V , Nicastro N , Frisoni GB , Lemstra AW , van der Zande J , Pilotto A , Padovani A , Garcia-Ptacek S , Savitcheva I , Ochoa-Figueroa MA , Davidsson A , Camacho V , Peira E , Arnaldi D , Bauckneht M , Pardini M , Sambuceti G , Vöglein J , Schnabel J , Unterrainer M , Perneczky R , Pogarell O , Buerger K , Catak C , Bartenstein P , Cumming P , Ewers M , Danek A , Levin J , Aarsland D , Nobili F , Rominger A , Brendel M

Movement disorders : official journal of the Movement Disorder Society - Dec 2019

Amyloid Load, Hippocampal Volume Loss, and Diffusion Tensor Imaging Changes in Early Phases of Brain Aging.

Haller S , Montandon ML , Rodriguez C , Garibotto V , Lilja J , Herrmann FR , Giannakopoulos P

Frontiers in neuroscience - 2019

Videos

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Contact

Département de radiologie et informatique médicale
Faculty of Medicine

Service de Médecine nucléaire et imagerie moléculaire, Département diagnostique
HUG
Email: valentina.garibotto@hcuge.ch