The goals of our Neuroscience and Neuroimaging Laboratory in Child and Adolescent Psychiatry are to study brain development and functioning in children, along with the influence of specific genetic factors on development. We aim at better understanding how genetic and brain alterations contribute to the emergence of cognitive or behavioral difficulties or psychiatric disorders during the course of development. Our research focuses on individuals who have genetic, neuropsychiatric or neurodevelopmental disorders, which result in behavior, learning or emotional regulation difficulties. A collaborative multidisciplinary approach that includes genetic, structural and functional neuroimaging and cognitive neuroscience has the following goals: a better definition of neurogenetic syndromes and conditions studied; identify markers of cognitive impairments; identify risk factors for psychiatric diseases and symptoms; use specific neurogenetic conditions as a homogeneous genetic model to better understand interactions between genes, brain, behavior and environmental factors in the etiopathogeny of neuropsychiatric diseases.
Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects.
Long-Lasting Rescue of Network and Cognitive Dysfunction in a Genetic Schizophrenia Model.
Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome.
Divergent default mode network connectivity during social perception in 22q11.2 deletion syndrome.
Département de psychiatrie