Group name: Neuroscience and Neuroimaging Laboratory in Child and Adolescent Psychiatry
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry
Domains: Development and Plasticity, Affective and Social Neurosciences
Keywords: child development, genetic, mental disorders
The goals of our Neuroscience and Neuroimaging Laboratory in Child and Adolescent Psychiatry are to study brain development and functioning in children, along with the influence of specific genetic factors on development. We aim at better understanding how genetic and brain alterations contribute to the emergence of cognitive or behavioral difficulties or psychiatric disorders during the course of development. Our research focuses on individuals who have genetic, neuropsychiatric or neurodevelopmental disorders, which result in behavior, learning or emotional regulation difficulties. A collaborative multidisciplinary approach that includes genetic, structural and functional neuroimaging and cognitive neuroscience has the following goals: a better definition of neurogenetic syndromes and conditions studied; identify markers of cognitive impairments; identify risk factors for psychiatric diseases and symptoms; use specific neurogenetic conditions as a homogeneous genetic model to better understand interactions between genes, brain, behavior and environmental factors in the etiopathogeny of neuropsychiatric diseases.
Multivariate patterns of disrupted sleep longitudinally predict affective vulnerability to psychosis in 22q11.2 Deletion Syndrome.
Amygdala subdivisions exhibit aberrant whole-brain functional connectivity in relation to stress intolerance and psychotic symptoms in 22q11.2DS.
Excitatory/Inhibitory Imbalance Underlies Hippocampal Atrophy in Individuals With 22q11.2 Deletion Syndrome With Psychotic Symptoms.
Updated clinical practice recommendations for managing children with 22q11.2 deletion syndrome.
Département de psychiatrie