Petra Huppi
Function: Professeure ordinaire
Group name: Child Development Disorders
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Paediatrics
Domains: Development and Plasticity
Keywords: brain development, brain injury, cerebral ischemia, intra-uterine growth restriction
Research activities
Our research includes clinical and fundamental neurosciences projects with the aim to use and develop neuro-imaging techniques for the study of normal and altered brain development in high-risk neonate and in animal models of brain injury.
Clinical: we use advanced MRI techniques and neuro-developmental assessment to look at the effects of intra-uterine growth restriction on structural and functional development of the brain.
Fundamental: In order to understand the alteration of brain development seen in high-risk infants, we have developed translational research of brain development compromise such as intra-uterine growth restriction or foetal exposition to adverse conditions and acute hypoxic-ischemic and inflammation brain injury in the newborn rat pup. Advanced magnetic resonance imaging and mechanistic evaluation technics are used to describe injury, healing and repair. These experimental paradigms allow us to study mechanisms of damage and repair in the developing brain.
Latest publications
Music impacts brain cortical microstructural maturation in very preterm infants: A longitudinal diffusion MR imaging study.
Corpus callosum structural characteristics in very preterm children and adolescents: Developmental trajectory and relationship to cognitive functioning.
The effect of mindfulness-based intervention on neurobehavioural functioning and its association with white-matter microstructural changes in preterm young adolescents.
Behavioral outcome of very preterm children at 5 years of age: Prognostic utility of brain tissue volumes at term-equivalent-age, perinatal, and environmental factors.
Videos
Contact
Département de pédiatrie
HUG
Email: Petra.Huppi@hcuge.ch
Stephane.Sizonenko@unige.ch (médecin adjoint du service)