Geneva University Neurocenter

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Petra Huppi

Affiliations: Geneva University Hospitals, Department of Paediatrics

Group name: Child Development Disorders

Domains: Development and Plasticity

Keywords: brain development, brain injury, cerebral ischemia, intra-uterine growth restriction

Research activities

Our research includes clinical and fundamental neurosciences projects with the aim to use and develop neuro-imaging techniques for the study of normal and altered brain development in high-risk neonate and in animal models of brain injury.

Clinical: we use advanced MRI techniques and neuro-developmental assessment to look at the effects of intra-uterine growth restriction on structural and functional development of the brain.

Fundamental: In order to understand the alteration of brain development seen in high-risk infants, we have developed translational research of brain development compromise such as intra-uterine growth restriction or foetal exposition to adverse conditions and acute hypoxic-ischemic and inflammation brain injury in the newborn rat pup. Advanced magnetic resonance imaging and mechanistic evaluation technics are used to describe injury, healing and repair. These experimental paradigms allow us to study mechanisms of damage and repair in the developing brain.

Latest publications

Early vocal contact and music in the NICU: new insights into preventive interventions.

Filippa M , Lordier L , De Almeida JS , Monaci MG , Adam-Darque A , Grandjean D , Kuhn P , Hüppi PS

Pediatric research - Jul 2019

Music in premature infants enhances high-level cognitive brain networks.

Lordier L , Meskaldji DE , Grouiller F , Pittet MP , Vollenweider A , Vasung L , Borradori-Tolsa C , Lazeyras F , Grandjean D , Van De Ville D , Hüppi PS

Proceedings of the National Academy of Sciences of the United States of America - Jun 2019

Pain, Parental Involvement, and Oxytocin in the Neonatal Intensive Care Unit.

Filippa M , Poisbeau P , Mairesse J , Monaci MG , Baud O , Hüppi P , Grandjean D , Kuhn P

Frontiers in psychology - 2019

Methodological consensus on clinical proton MRS of the brain: Review and recommendations.

Wilson M , Andronesi O , Barker PB , Bartha R , Bizzi A , Bolan PJ , Brindle KM , Choi IY , Cudalbu C , Dydak U , Emir UE , Gonzalez RG , Gruber S , Gruetter R , Gupta RK , Heerschap A , Henning A , Hetherington HP , Huppi PS , Hurd RE , Kantarci K , Kauppinen RA , Klomp DWJ , Kreis R , Kruiskamp MJ , Leach MO , Lin AP , Luijten PR , Marjańska M , Maudsley AA , Meyerhoff DJ , Mountford CE , Mullins PG , Murdoch JB , Nelson SJ , Noeske R , Öz G , Pan JW , Peet AC , Poptani H , Posse S , Ratai EM , Salibi N , Scheenen TWJ , Smith ICP , Soher BJ , Tkáč I , Vigneron DB , Howe FA

Magnetic resonance in medicine - Aug 2019

Videos

La musique améliore le développement du cerveau des prématurés

Les troubles du comportement sont en augmentation chez les écoliers

A quoi pensent les bébés?

Contact

Département de pédiatrie
HUG
Email: Petra.Huppi@hcuge.ch
Stephane.Sizonenko@unige.ch (médecin adjoint du service)