Most of research programs developed in our group are focused on perinatal brain injury and aim at preventing brain injury associated with premature birth or intra-uterine growth retardation. We are currently developing basic research programs including :
1- Perinatal microvasculature development in vivo and changes of gene expression controlling angiogenesis in animal models replicating perinatal brain injury.
2- Vasoreactivity and intrinsic brain connectivity of the developing brain in response to the genetic modulation of oxytocin CNS secretion from ParaVentricular Nucleus and remote modulation of microglial activation within the developing white matter.
3- Effect of sensorimotor interventions in the neonatal rat on regional blood volume changes and in vivo cortical connectivity using a new functional brain imaging modality (Ultrafast Doppler).
Brain perfusion imaging in neonates.
Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice.
Nebulized curcumin protects neonatal lungs from antenatal insult in rats.
Survival without Bronchopulmonary Dysplasia of Extremely Preterm Infants: A Predictive Model at Birth.
Département de pédiatrie