Olivier Baud

Group name: Pathogenesis of perinatal brain damage and neuroprotection of the developing brain

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Paediatrics

Keywords: angiogenesis, brain development, brain imaging, brain lesions, cortical connectivity

Research activities

Most of research programs developed in our group are focused on perinatal brain injury and aim at preventing brain injury associated with premature birth or intra-uterine growth retardation. We are currently developing basic research programs including :

1- Perinatal microvasculature development in vivo and changes of gene expression controlling angiogenesis in animal models replicating perinatal brain injury.

2- Vasoreactivity and intrinsic brain connectivity of the developing brain in response to the genetic modulation of oxytocin CNS secretion from ParaVentricular Nucleus and remote modulation of microglial activation within the developing white matter.

3- Effect of sensorimotor interventions in the neonatal rat on regional blood volume changes and in vivo cortical connectivity using a new functional brain imaging modality (Ultrafast Doppler).

Latest publications

The Role of Oxytocin in Abnormal Brain Development: Effect on Glial Cells and Neuroinflammation.

Knoop M , Possovre ML , Jacquens A , Charlet A , Baud O , Darbon P

Cells - Dec 2022

Neurocognitive outcomes at age 5 years after prophylactic hydrocortisone in infants born extremely preterm.

Trousson C , Toumazi A , Bourmaud A , Biran V , Baud O

Developmental medicine and child neurology - Nov 2022

Risk factors for unfavorable outcome at discharge of newborns with hypoxic-ischemic encephalopathy in the era of hypothermia.

Debillon T , Sentilhes L , Kayem G , Chevallier M , Zeitlin J , Baud O , Vilotitch A , Pierrat V , Guellec I , Ancel PY , Bednarek N , Ego A

Pediatric research - Oct 2022

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial.

Schmitz T , Doret-Dion M , Sentilhes L , Parant O , Claris O , Renesme L , Abbal J , Girault A , Torchin H , Houllier M , Le Saché N , Vivanti AJ , De Luca D , Winer N , Flamant C , Thuillier C , Boileau P , Blanc J , Brevaut V , Bouet PE , Gascoin G , Beucher G , Datin-Dorriere V , Bounan S , Bolot P , Poncelet C , Alberti C , Ursino M , Aupiais C , Baud O , ,

Lancet (London, England) - Aug 2022

See the complete list of the publications

Videos

La musique améliore le développement du cerveau des prématurés

Contact

Département de pédiatrie

HUG

olivier.baud@unige.ch