Most of research programs developed in our group are focused on perinatal brain injury and aim at preventing brain injury associated with premature birth or intra-uterine growth retardation. We are currently developing basic research programs including :
1- Perinatal microvasculature development in vivo and changes of gene expression controlling angiogenesis in animal models replicating perinatal brain injury.
2- Vasoreactivity and intrinsic brain connectivity of the developing brain in response to the genetic modulation of oxytocin CNS secretion from ParaVentricular Nucleus and remote modulation of microglial activation within the developing white matter.
3- Effect of sensorimotor interventions in the neonatal rat on regional blood volume changes and in vivo cortical connectivity using a new functional brain imaging modality (Ultrafast Doppler).
Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury.
Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia.
Modulation of Microglial Activation by Adenosine A2a Receptor in Animal Models of Perinatal Brain Injury.
A Model of Perinatal Ischemic Stroke in the Rat: 20 Years Already and What Lessons?
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