The main activity of our unit is to propose surgical solution to drug resistant patient. Among all functional brain imaging techniques, ESI (Electromagnetic Source Imaging) is precise and useful to localize the epileptic foci.Our group demonstrated that high resolution EEG (256 channels) is promised tool to localize epileptic foci for various type of epilepsy. Multimodal imaging allow us to compare the yield of each technique (MRI, PET, SPECT, ESI, fMRI) for different group of patient (paediatric population, non lesional epilepsy).
Deep brain stimulation (DBS) is emerging as a possible treatment for intractable epilepsy, affecting 0.2-0.3% of the population. We aim at determining the minimal and most efficient stimulation that is required to prevent seizures and that guarantees a safe stimulation. Our group is also involved in program research to better understand epilepsy mechanisms. Then genetic, development and genesis of epilepsy are part of our centres of interest.
Postoperative memory prognosis in temporal lobe epilepsy surgery: The contribution of postictal memory.
Human amygdala response to unisensory and multisensory emotion input: No evidence for superadditivity from intracranial recordings.
The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates.
Neurophysiological evidence for early modulation of amygdala activity by emotional reappraisal.
Département des neurosciences cliniques