The main activity of our unit is to propose surgical solution to drug resistant patient. Among all functional brain imaging techniques, ESI (Electromagnetic Source Imaging) is precise and useful to localize the epileptic foci.Our group demonstrated that high resolution EEG (256 channels) is promised tool to localize epileptic foci for various type of epilepsy. Multimodal imaging allow us to compare the yield of each technique (MRI, PET, SPECT, ESI, fMRI) for different group of patient (paediatric population, non lesional epilepsy).
Deep brain stimulation (DBS) is emerging as a possible treatment for intractable epilepsy, affecting 0.2-0.3% of the population. We aim at determining the minimal and most efficient stimulation that is required to prevent seizures and that guarantees a safe stimulation. Our group is also involved in program research to better understand epilepsy mechanisms. Then genetic, development and genesis of epilepsy are part of our centres of interest.
Nicotinic receptor abnormalities as a biomarker in idiopathic generalized epilepsy.
Audio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study.
MP2RAGE and Susceptibility-Weighted Imaging in Lesional Epilepsy at 7T.
Electrophysiological Evidence for the Development of a Self-Sustained Large-Scale Epileptic Network in the Kainate Mouse Model of Temporal Lobe Epilepsy.
Département des neurosciences cliniques