Laszlo Vutskits

Group name: Neuroscience-oriented Anesthesia Research Group

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Anaesthetics, Pharmacology and Intensive Care

Domains: Development and Plasticity

Keywords: anesthesia, brain development, neurotransmission

Research activities

Every year, a large number of human fetuses and infants receive anesthesia worldwide. Anesthetics interfere with GABAergic and glutamatergic neurotransmissions that play a critical role in brain development. Our major research interest is to evaluate the impact of anesthetics on the developing central nervous system (CNS). We primarily focus on neuronal dendritic development and seek to elucidate whether exposure to anesthetics induce adverse effects on neuronal differentiation during the early postnatal period. For this purpose, we use in vitro and in vivo models of dendritic differentiation as well as various morphological and functional techniques including confocal imaging, quantitative dendritic arbor analysis and laser capture microdissection.

Group website

Latest publications

Core outcome sets for pediatric perioperative research: An international stakeholder engagement exercise and consensus report from the Pediatric Perioperative Outcomes Group.

Stricker PA , Vutskits L , de Graaff JC , von Ungern-Sternberg BS , Goobie SM , Zuo YX , Ramos TA , Meyer HM , Taylor EM , Whyte SD , Malic CC , Echeverry PC , Muhly WT , Xie DY , Walker SM , Razavi C , Torborg AM , Cravero JP , Kurth CD , Rawlinson E , Yang L , Xu T , Graham MR , Seal R , Sommerfield A , Davidson AJ

Anesthesiology - Jul 2025

Quantitative electroencephalogram and machine learning to predict expired sevoflurane concentration in infants.

Kumar R , Skowno J , von Ungern-Sternberg BS , Davidson A , Xu T , Zhang J , Song X , Zhang M , Zhao P , Liu H , Jiang Y , Zuo Y , de Graaff JC , Vutskits L , Olbrecht VA , Szmuk P , Simpao AF , Tsui FR , Pratap JN , Padiyath A , Nelson O , Kurth CD , Yuan I ,

Journal of clinical monitoring and computing - May 2025

Assessing Sleep: A New Biomarker for Developmental Anesthesia Neurotoxicity Research?

Vutskits L , Goldstein PA

Anesthesia and analgesia - Apr 2025

Ventilation strategies and risk factors for intraoperative respiratory critical events and postoperative pulmonary complications in neonates and small infants: a secondary analysis of the NECTARINE cohort.

Fuchs A , Disma N , Engelhardt T , Marchesini V , Riedel T , Boda K , Habre W , Riva T , , Disma N , Veyckemans F , Virag K , Hansen TG , Becke-Jakob K , Harlet P , Vutskits L , Walker SM , de Graaff JC , Zielinska M , Simic D , Engelhardt T , Habre W ,

British journal of anaesthesia - Feb 2025

See the complete list of the publications

Contact

Département d’anesthésiologie, pharmacologie et soins intensifs
HUG
Email: Laszlo.Vutskits@hcuge.ch