Karl Schaller
Function: Professeur ordinaire
Group name: Geneva Neuro-glia-vascular Lab
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Clinical Neurosciences
Domains: Development and Plasticity
Keywords: brain injury, glia, neuroprotection, stroke
Research activities
The main interest of our lab is to better understand the neuro-glia-vascular physiology in the normal and pathological brain. Our research focuses on the 3 most important cell types in the brain: neuron, astrocyte and endothelial cell. These cells are affected after stroke or brain trauma. Our aim is to investigate how these cells interacts using in vitro and in vivo models. This understanding is important for the development of new neuroprotective and restorative therapies. The group of Prof K. Schaller is comprised of three teams working on specific aspects of the neuro-glio-vascular unit. (Dr Bijlenga’s team, interested in intracellular calcium modifications in neurones and glia during ischemia ; Dr Badaut’s team, the role of the astrocyte in the brain water and energy homeostasis ; Dr da Silva’s team, the role of L-arginine/arginase pathway in the autocrine and paracrine regulation of the cell types present in the neuromuscular unit ; Dr Schatlo, investigating molecular mechanisms of brain damage following cerebral vasospasm following subarachnoid hemorrhage and stroke.)
Latest publications
Odontoid Fractures: A Review of the Current State of the Art.
Brain Metastases from Genito-Urinary Cancers in the Canton of Geneva (Switzerland): Study of Incidence, Management and Outcomes.
Self-other voice discrimination task: A potential neuropsychological tool for clinical assessment of self-related deficits.
Changes in cortical thickness: yet another indication of supraspinal adaptations in degenerative cervical myelopathy.
Videos
Contact
Département des neurosciences cliniques
HUG
Email: Karl.Schaller@hcuge.ch