Nathalie Ginovart
Function: Professeure associée
Group name: Individual Differences and Vulnerability to Addiction
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry
Domains: Attention and Cognition
Keywords: addictive behaviors, behavioral addiction
Research activities
Understanding how and why certain individuals have a greater propensity to develop addictive behaviors remains a major challenge in neuroscience. Our lab is interested in investigating the risk factors and underlying neural correlates conferring a predisposition to addictive disorders (drug and behavioral addictions) and related neuropsychiatric illnesses. More specifically, we focus on understanding the contribution and interplay of behavioral trait variables considered important in the psychopathologies of addictions – impulsivity, novelty seeking and risky-decision making – and neurochemical dysregulations of the mesocorticolimbic dopamine system to the development of addictive disorders. We use a cross-species translational approach combining behavioral testing with in vivo molecular imaging techniques in human and animal models, associated with pharmacological and genetic tools in rodents.
Latest publications
Activation of the mPFC-NAc Pathway Reduces Motor Impulsivity but Does Not Affect Risk-Related Decision-Making in Innately High-Impulsive Male Rats.
Dissociable Roles of the mPFC-to-VTA Pathway in the Control of Impulsive Action and Risk-Related Decision-Making in Roman High- and Low-Avoidance Rats.
Decoupling Dopamine Synthesis from Impulsive Action, Risk-Related Decision-Making, and Propensity to Cocaine Intake: A Longitudinal [F]-FDOPA PET Study in Roman High- and Low-Avoidance Rats.
Repeated Cocaine Intake Differentially Impacts Striatal D Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse.
Hide the members of the Lab
Prof. Nathalie Ginovart
+41 22 37 95 366
nathalie.ginovart@unige.ch
Raphaël Goutaudier
+41 22 37 95 377
raphael.goutaudier@unige.ch
Florian Gilhet--Marchessaux
+41 22 37 95 377
florian.gilhet--marchessaux@unige.ch
Laura Rodriguez Peris
+41 22 37 95 377
laura.rodriguezperis@unige.ch
Contact
Département de psychiatrie
Département des neurosciences fondamentales
HUG
Email: Nathalie.Ginovart@unige.ch