Giovanni Frisoni
Group name: Laboratory of Neuroimaging of Aging
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry
Domains: Development and Plasticity
Keywords: Alzheimer's disease, biomarkers, health care
Research activities
The group has over 20 years of experience in clinical and translational research on Alzheimer’s disease. The main scientific interest is the use of neuroimaging techniques and other biomarkers in persons with or at risk for cognitive impairment. Acquisitions and innovations in fundamental neurosciences, ICT, and technology are uptaken and translated for use into a clinical setting for better pathophysiological understanding, diagnosis, prognosis, disease tracking, drug therapy, and rehabilitation. Specific topics of investigation are: the clinical use of imaging and fluid biomarkers; in vivo neurobiology of Alzheimer’s disease; the clinical use of innovative PET ligands; harmonisation of imaging markers for clinical use; development of innovative image analysis environments based on advanced ICT technology.
Latest publications
[18F]flutemetamol uptake in the colon of a memory clinic population and its association with brain amyloidosis and the gut microbiota profile: an exploratory study.
Microstructural assessment of the locus coeruleus-entorhinal cortex pathway and association with ATN markers in cognitive impairment.
Resilience in Alzheimer's disease: Impact of operationalization and methodological choices.
The science does not yet support regulatory approval of amyloid-targeting therapies for Alzheimer's disease based solely on biomarker evidence.
Contact
Département de psychiatrie
HUG
Email: Giovanni.Frisoni@hcuge.ch