Armand Savioz

Armand Savioz

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry

Group name: NEURAD

Domains: Development and Plasticity

Keywords: Alzheimer's disease, degenerative dementia, synapse

Research activities

Our studies deal with molecular mechanisms (e.g. synaptic beta-amyloid hypothesis) involved in vulnerability of neural networks in aging as well as in degenerative dementia (Alzheimer disease and frontotemporal dementia). Starting from observations made in humans, cellular and murine models are used to investigate how synaptic modifications and loss lead to functional alterations according to a synapto-connectionist paradigm, but may be counteracted by cerebral reserve and compensatory mechanisms.

Latest publications

Contact

Département de psychiatrie
HUG
Email: Armand.Savioz@hcuge.ch