Neurological and cognitive deficits are frequent and highly disabling. Intensive training and rehabilitation can lead to improvement, but the selection of efficient treatment strategies for the individual patient is often difficult because of insufficient knowledge about how the human brain can recover lost functions. We make use of recent advances in neuroimaging techniques to non-invasively assess the network organization of the brain and to optimize treatment of patients with brain lesions. In particular, we aim to: – characterize the changes in brain network organization induced by focal lesions or diffuse degeneration; – visualize the mechanisms underlying functional recovery; – identify prognostic factors; – assess the effect of novel treatment approaches that might improve recovery, such as transcranial stimulation, neuro-feedback, and others. Functional imaging and advanced signal analysis techniques are also used to investigate the mechanisms of human cognition and behavior such as: decision-making, introspection, and yawning.
Transcranial direct current stimulation reduces secondary white-matter degradation after stroke.
Resting-state connectivity after visuo-motor skill learning is inversely associated with offline consolidation in Parkinson's disease and healthy controls.
Heartbeat-enhanced immersive virtual reality to treat complex regional pain syndrome.
Focal versus distributed temporal cortex activity for speech sound category assignment.
Département des neurosciences cliniques