Jean-Michel Aubry

Jean-Michel Aubry

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry

Group name: Neuroendocrinology, psychopharmacology and mood disorders

Domains: Affective and Social Neurosciences, Development and Plasticity

Keywords: anxiety, bipolar, depression, mental disorders, stress

Research activities

The main research interest of our group is on the neurobiology of mood disorders with a focus on the links between neuroendocrinology, stress and depression, specifically hypothalamo-hypophyso-adrenal system dysfunctions and the risk of depressive relapse. These issues are explored with pre-clinical models as well as with clinical research protocols. In collaboration with other groups in Geneva and abroad, another topic of research is addressing the mode of action of mood stabilizers with in vitro paradigms. Finally, more recently, genetic studies on unipolar and bipolar disorders have also been initiated in collaboration with other groups. Our group is now part of several international consortium evaluating the genetic basis of antidepressants and lithium response vs non-response.

Latest publications

Characterisation of age and polarity at onset in bipolar disorder.

Kalman JL , Olde Loohuis LM , Vreeker A , McQuillin A , Stahl EA , Ruderfer D , Grigoroiu-Serbanescu M , Panagiotaropoulou G , Ripke S , Bigdeli TB , Stein F , Meller T , Meinert S , Pelin H , Streit F , Papiol S , Adams MJ , Adolfsson R , Adorjan K , Agartz I , Aminoff SR , Anderson-Schmidt H , Andreassen OA , Ardau R , Aubry JM , Balaban C , Bass N , Baune BT , Bellivier F , Benabarre A , Bengesser S , Berrettini WH , Boks MP , Bromet EJ , Brosch K , Budde M , Byerley W , Cervantes P , Chillotti C , Cichon S , Clark SR , Comes AL , Corvin A , Coryell W , Craddock N , Craig DW , Croarkin PE , Cruceanu C , Czerski PM , Dalkner N , Dannlowski U , Degenhardt F , Del Zompo M , DePaulo JR , Djurovic S , Edenberg HJ , Eissa MA , Elvsåshagen T , Etain B , Fanous AH , Fellendorf F , Fiorentino A , Forstner AJ , Frye MA , Fullerton JM , Gade K , Garnham J , Gershon E , Gill M , Goes FS , Gordon-Smith K , Grof P , Guzman-Parra J , Hahn T , Hasler R , Heilbronner M , Heilbronner U , Jamain S , Jimenez E , Jones I , Jones L , Jonsson L , Kahn RS , Kelsoe JR , Kennedy JL , Kircher T , Kirov G , Kittel-Schneider S , Klöhn-Saghatolislam F , Knowles JA , Kranz TM , Lagerberg TV , Landen M , Lawson WB , Leboyer M , Li QS , Maj M , Malaspina D , Manchia M , Mayoral F , McElroy SL , McInnis MG , McIntosh AM , Medeiros H , Melle I , Milanova V , Mitchell PB , Monteleone P , Monteleone AM , Nöthen MM , Novak T , Nurnberger JI , O'Brien N , O'Connell KS , O'Donovan C , O'Donovan MC , Opel N , Ortiz A , Owen MJ , Pålsson E , Pato C , Pato MT , Pawlak J , Pfarr JK , Pisanu C , Potash JB , Rapaport MH , Reich-Erkelenz D , Reif A , Reininghaus E , Repple J , Richard-Lepouriel H , Rietschel M , Ringwald K , Roberts G , Rouleau G , Schaupp S , Scheftner WA , Schmitt S , Schofield PR , Schubert KO , Schulte EC , Schweizer B , Senner F , Severino G , Sharp S , Slaney C , Smeland OB , Sobell JL , Squassina A , Stopkova P , Strauss J , Tortorella A , Turecki G , Twarowska-Hauser J , Veldic M , Vieta E , Vincent JB , Xu W , Zai CC , Zandi PP , , , , Di Florio A , Smoller JW , Biernacka JM , McMahon FJ , Alda M , Müller-Myhsok B , Koutsouleris N , Falkai P , Freimer NB , Andlauer TFM , Schulze TG , Ophoff RA
The British journal of psychiatry : the journal of mental science - Dec 2021

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.

Schubert KO , Thalamuthu A , Amare AT , Frank J , Streit F , Adl M , Akula N , Akiyama K , Ardau R , Arias B , Aubry JM , Backlund L , Bhattacharjee AK , Bellivier F , Benabarre A , Bengesser S , Biernacka JM , Birner A , Marie-Claire C , Cearns M , Cervantes P , Chen HC , Chillotti C , Cichon S , Clark SR , Cruceanu C , Czerski PM , Dalkner N , Dayer A , Degenhardt F , Del Zompo M , DePaulo JR , Étain B , Falkai P , Forstner AJ , Frisen L , Frye MA , Fullerton JM , Gard S , Garnham JS , Goes FS , Grigoroiu-Serbanescu M , Grof P , Hashimoto R , Hauser J , Heilbronner U , Herms S , Hoffmann P , Hou L , Hsu YH , Jamain S , Jiménez E , Kahn JP , Kassem L , Kuo PH , Kato T , Kelsoe J , Kittel-Schneider S , Ferensztajn-Rochowiak E , König B , Kusumi I , Laje G , Landén M , Lavebratt C , Leboyer M , Leckband SG , Maj M , , Manchia M , Martinsson L , McCarthy MJ , McElroy S , Colom F , Mitjans M , Mondimore FM , Monteleone P , Nievergelt CM , Nöthen MM , Novák T , O'Donovan C , Ozaki N , Ösby U , Papiol S , Pfennig A , Pisanu C , Potash JB , Reif A , Reininghaus E , Rouleau GA , Rybakowski JK , Schalling M , Schofield PR , Schweizer BW , Severino G , Shekhtman T , Shilling PD , Shimoda K , Simhandl C , Slaney CM , Squassina A , Stamm T , Stopkova P , Tekola-Ayele F , Tortorella A , Turecki G , Veeh J , Vieta E , Witt SH , Roberts G , Zandi PP , Alda M , Bauer M , McMahon FJ , Mitchell PB , Schulze TG , Rietschel M , Baune BT
Translational psychiatry - Nov 2021

HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders.

Le Clerc S , Lombardi L , Baune BT , Amare AT , Schubert KO , Hou L , Clark SR , Papiol S , Cearns M , Heilbronner U , Degenhardt F , Tekola-Ayele F , Hsu YH , Shekhtman T , Adli M , Akula N , Akiyama K , Ardau R , Arias B , Aubry JM , Backlund L , Bhattacharjee AK , Bellivier F , Benabarre A , Bengesser S , Biernacka JM , Birner A , Brichant-Petitjean C , Cervantes P , Chen HC , Chillotti C , Cichon S , Cruceanu C , Czerski PM , Dalkner N , Dayer A , Del Zompo M , DePaulo JR , Étain B , Jamain S , Falkai P , Forstner AJ , Frisen L , Frye MA , Fullerton JM , Gard S , Garnham JS , Goes FS , Grigoroiu-Serbanescu M , Grof P , Hashimoto R , Hauser J , Herms S , Hoffmann P , Jiménez E , Kahn JP , Kassem L , Kuo PH , Kato T , Kelsoe JR , Kittel-Schneider S , Ferensztajn-Rochowiak E , König B , Kusumi I , Laje G , Landén M , Lavebratt C , Leckband SG , Tortorella A , Manchia M , Martinsson L , McCarthy MJ , McElroy SL , Colom F , Millischer V , Mitjans M , Mondimore FM , Monteleone P , Nievergelt CM , Nöthen MM , Novák T , O'Donovan C , Ozaki N , Ösby U , Pfennig A , Potash JB , Reif A , Reininghaus E , Rouleau GA , Rybakowski JK , Schalling M , Schofield PR , Schweizer BW , Severino G , Shilling PD , Shimoda K , Simhandl C , Slaney CM , Pisanu C , Squassina A , Stamm T , Stopkova P , Maj M , Turecki G , Vieta E , Veeh J , Witt SH , Wright A , Zandi PP , Mitchell PB , Bauer M , Alda M , Rietschel M , McMahon FJ , Schulze TG , Spadoni JL , Boukouaci W , Richard JR , Le Corvoisier P , Barrau C , Zagury JF , Leboyer M , Tamouza R
Scientific reports - 09 2021
See the complete list of the publications

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Contact

Département de psychiatrie
HUG
Email: Jean-Michel.Aubry@hcuge.ch