Jean-Michel Aubry
Affiliations: Geneva University Hospitals, Department of Psychiatry
Group name: Neuroendocrinology, psychopharmacology and mood disorders
Domains: Affective and Social Neurosciences, Development and Plasticity
Keywords: anxiety, bipolar, depression, mental disorders, stress
Research activities
The main research interest of our group is on the neurobiology of mood disorders with a focus on the links between neuroendocrinology, stress and depression, specifically hypothalamo-hypophyso-adrenal system dysfunctions and the risk of depressive relapse. These issues are explored with pre-clinical models as well as with clinical research protocols. In collaboration with other groups in Geneva and abroad, another topic of research is addressing the mode of action of mood stabilizers with in vitro paradigms. Finally, more recently, genetic studies on unipolar and bipolar disorders have also been initiated in collaboration with other groups. Our group is now part of several international consortium evaluating the genetic basis of antidepressants and lithium response vs non-response.
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Latest publications
Increased Reactivity of the Mesolimbic Reward System after Ketamine Injection in Patients with Treatment-resistant Major Depressive Disorder.
Rumination related activity in brain networks mediating attentional switching in euthymic bipolar patients.
Efficacy and Safety of a Rapid Intravenous Injection of Ketamine 0.5 mg/kg in Treatment-Resistant Major Depression: An Open 4-Week Longitudinal Study.
Impulsivity and its association with childhood trauma experiences across bipolar disorder, attention deficit hyperactivity disorder and borderline personality disorder.
Videos
Contact
Département de psychiatrie
HUG
Email: Jean-Michel.Aubry@hcuge.ch
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