Alexandre Dayer

Alexandre Dayer

Affiliations: Faculty of Medecine, Department of Basic Neurosciences

Group name: Psychiatry and Developmental Neuroplasticity

Domains: Development and Plasticity

Keywords: brain development, migrating neurons, psychiatric disorders

Research activities

Neurodevelopmental abnormalities are thought to play a key role in the etiology of major psychiatric disorders such as bipolar disorder and schizophrenia. Among these developmental abnormalities, defects in the migration and differentiation of GABAergic interneurons have been suggested. In the laboratory we aim to study psychiatric-relevant molecular factors that control the migration and differentiation of cortical GABAergic interneurons during the embyronic period and the early postnatal period. For this purpose, we use mutant mice for genes implicated in cortical development as well as transgenic mice expressing GFP in cortical GABAergic interneurons. We apply a broad array of techniques including in vitro migration essays and confocal live imaging to directly monitor interneuron migration in cortical slices.

Group website

Latest publications

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.

Kalman JL , Papiol S , Forstner AJ , Heilbronner U , Degenhardt F , Strohmaier J , Adli M , Adorjan K , Akula N , Alda M , Anderson-Schmidt H , Andlauer TF , Anghelescu IG , Ardau R , Arias B , Arolt V , Aubry JM , Backlund L , Bartholdi K , Bauer M , Baune BT , Becker T , Bellivier F , Benabarre A , Bengesser S , Bhattacharjee AK , Biernacka JM , Birner A , Brichant-Petitjean C , Budde M , Cervantes P , Chillotti C , Cichon S , Clark SR , Colom F , Comes AL , Cruceanu C , Czerski PM , Dannlowski U , Dayer A , Del Zompo M , DePaulo JR , Dietrich DE , Étain B , Ethofer T , Falkai P , Fallgatter A , Figge C , Flatau L , Folkerts H , Frisen L , Frye MA , Fullerton JM , Gade K , Gard S , Garnham JS , Goes FS , Grigoroiu-Serbanescu M , Gryaznova A , Hake M , Hauser J , Herms S , Hoffmann P , Hou L , Jäger M , Jamain S , Jiménez E , Juckel G , Kahn JP , Kassem L , Kelsoe J , Kittel-Schneider S , Kliwicki S , Klohn-Sagatholislam F , Koller M , König B , Konrad C , Lackner N , Laje G , Landén M , Lang FU , Lavebratt C , Leboyer M , Leckband SG , Maj M , Manchia M , Martinsson L , McCarthy MJ , McElroy SL , McMahon FJ , Mitchell PB , Mitjans M , Mondimore FM , Monteleone P , Nieratschker V , Nievergelt CM , Novák T , Ösby U , Pfennig A , Potash JB , Reich-Erkelenz D , Reif A , Reimer J , Reininghaus E , Reitt M , Ripke S , Rouleau GA , Rybakowski JK , Schalling M , Scherk H , Schmauß M , Schofield PR , Schubert KO , Schulte EC , Schulz S , Senner F , Severino G , Shekhtman T , Shilling PD , Simhandl C , Slaney CM , Spitzer C , Squassina A , Stamm T , Stegmaier S , Stierl S , Stopkova P , Thiel A , Tighe SK , Tortorella A , Turecki G , Vieta E , Veeh J , von Hagen M , Wigand ME , Wiltfang J , Witt S , Wright A , Zandi PP , Zimmermann J , Nöthen M , Rietschel M , Schulze TG
Bipolar disorders - Feb 2019

Contact

Département de psychiatrie
HUG
Email: Alexandre.Dayer@unige.ch