Valentina Garibotto

Function: Professeure associée

Nom du groupe: Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTLab)

Group type: Main

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Radiology and Medical Informatics

Mot clés: biomarkers, molecular neuroimaging, neurodegeneration, neurotransmission

Activités de recherche

Our research group works on molecular neuroimaging, a tool allowing the in vivo measurement of protein deposits, brain metabolism and neurotransmission. Molecular imaging has changed the way we understand brain disorders, especially those associated with neurodegeneration. In this field, the current gold standard is still neuropathology at post-mortem: this represents an intrinsic limitation for the development and assessment of targeted therapies. The availability of in vivo biomarkers of the disease, among these molecular imaging, finally offers an opportunity for precision medicine in degenerative disorders and has already changed how we evaluate patients and how we test new drugs. Our group benefits from a unique and privileged position, on one hand working in close collaboration with various research groups at the Geneva University and abroad and on the other hand being embedded in a clinical division of the Geneva University Hospitals for patient diagnosis and care. This position allows us to translate new ideas and knowledge, coming from basic and applied research programs, into procedures that can be tested in clinical studies and validated for clinical practice.

Dernières publications

Early-phase F-Flortaucipir tau-PET as a proxy of brain metabolism in Alzheimer's disease: a comparison with F-FDG-PET and early-phase amyloid-PET.

Boccalini C , Peretti DE , Mathoux G , Iaccarino L , Ribaldi F , Scheffler M , Perani D , Frisoni GB , Garibotto V

European journal of nuclear medicine and molecular imaging - Jan 2025

In Vivo Tau and Neurodegeneration Imaging in a Family With the Presenilin 1 Met146Leu Pathogenic Variant.

Boccalini C , Dodich A , Scheffler M , Laganà V , Fratto E , Frisoni GB , Bruni AC , Colao R , Perani D , Garibotto V

Neurology - Dec 2024

Centiloid recommendations for clinical context-of-use from the AMYPAD consortium.

Collij LE , Bollack A , La Joie R , Shekari M , Bullich S , Roé-Vellvé N , Koglin N , Jovalekic A , Garciá DV , Drzezga A , Garibotto V , Stephens AW , Battle M , Buckley C , Barkhof F , Farrar G , Gispert JD ,

Alzheimer's & dementia : the journal of the Alzheimer's Association - Dec 2024

Quantification Supports Amyloid PET Visual Assessment of Challenging Cases: Results from the AMYPAD Diagnostic and Patient Management Study.

Collij LE , Bischof GN , Altomare D , Bader I , Battle M , Vállez García D , Lopes Alves I , Wolz R , Gismondi R , Stephens A , Walker Z , Scheltens P , Nordberg A , Gispert JD , Drzezga A , Perissinotti A , Morbelli S , Buckley C , Garibotto V , Frisoni GB , Farrar G , Barkhof F ,

Journal of nuclear medicine : official publication, Society of Nuclear Medicine - Jan 2025

See the complete list of the publications

Videos

Alzheimer, où en est-on ?

Contact

Département de radiologie et informatique médicale
Faculty of Medicine

Service de Médecine nucléaire et imagerie moléculaire, Département diagnostique
HUG
Email: valentina.garibotto@hcuge.ch