Philippe Millet

Philippe Millet

Function: Professeur associé

Nom du groupe: PET and SPECT Quantification

Group type: Main

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry

Domaines: Development and Plasticity

Mot clés: neuroimaging, PET/SPECT, radioligand

Activités de recherche

Our research projects focus on various themes of neuroimaging including the development of quantitative imaging methods in PET/SPECT for the study of different cerebral neurotransmission systems and neuroinflammation using various PET/SPECT TSPO tracers. We are interested in preclinical PET/SPECT applications and the mechanism of action of atypical antipsychotics. We also study of neuroinflammation in relation to amyloid deposits and behavioral and cognitive alterations in transgenic models of Alzheimer’s disease. In vitro studies on the post-mortem human brain are also performed in ou lab for the identification and characterization of inflammation with respect to neurodegenerative pathologies. We are also interested in the clinical application of the neuroinflammatory process in various psychiatric pathologies

Dernières publications

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.

Nutma E , Fancy N , Weinert M , Tsartsalis S , Marzin MC , Muirhead RCJ , Falk I , Breur M , de Bruin J , Hollaus D , Pieterman R , Anink J , Story D , Chandran S , Tang J , Trolese MC , Saito T , Saido TC , Wiltshire KH , Beltran-Lobo P , Phillips A , Antel J , Healy L , Dorion MF , Galloway DA , Benoit RY , Amossé Q , Ceyzériat K , Badina AM , Kövari E , Bendotti C , Aronica E , Radulescu CI , Wong JH , Barron AM , Smith AM , Barnes SJ , Hampton DW , van der Valk P , Jacobson S , Howell OW , Baker D , Kipp M , Kaddatz H , Tournier BB , Millet P , Matthews PM , Moore CS , Amor S , Owen DR
Nature communications - Aug 2023
See the complete list of the publications


Département de psychiatrie