Philippe Millet
Function: Professeur associé
Nom du groupe: PET and SPECT Quantification
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry
Domaines: Development and Plasticity
Mot clés: neuroimaging, PET/SPECT, radioligand
Activités de recherche
Our research projects focus on various themes of neuroimaging including the development of quantitative imaging methods in PET/SPECT for the study of different cerebral neurotransmission systems and neuroinflammation using various PET/SPECT TSPO tracers. We are interested in preclinical PET/SPECT applications and the mechanism of action of atypical antipsychotics. We also study of neuroinflammation in relation to amyloid deposits and behavioral and cognitive alterations in transgenic models of Alzheimer’s disease. In vitro studies on the post-mortem human brain are also performed in ou lab for the identification and characterization of inflammation with respect to neurodegenerative pathologies. We are also interested in the clinical application of the neuroinflammatory process in various psychiatric pathologies
Dernières publications
Chemogenetic activation of oxytocinergic neurons modulates acute neuroinflammation and improves brain development after pediatric traumatic brain injury.
Glial cells are involved in day-night protein dysregulation in the hippocampus of a mouse model of Alzheimer's disease.
TSPO contributes to neuropathology and cognitive deficits in Alzheimer's disease.
Brain, CSF, and Blood Metabolomics Signature in the TgF344-AD Rat Model of Alzheimer's Disease.
Contact
Département de psychiatrie
HUG
Email: Philippe.Millet@hcuge.ch