Activités de recherche
Most of research programs developed in our group are focused on perinatal brain injury and aim at preventing brain injury associated with premature birth or intra-uterine growth retardation. We are currently developing basic research programs including :
1- Perinatal microvasculature development in vivo and changes of gene expression controlling angiogenesis in animal models replicating perinatal brain injury.
2- Vasoreactivity and intrinsic brain connectivity of the developing brain in response to the genetic modulation of oxytocin CNS secretion from ParaVentricular Nucleus and remote modulation of microglial activation within the developing white matter.
3- Effect of sensorimotor interventions in the neonatal rat on regional blood volume changes and in vivo cortical connectivity using a new functional brain imaging modality (Ultrafast Doppler).
Impact of Fetal Growth Restriction on the Neonatal Microglial Proteome in the Rat.
Early arterial pressure monitoring and term-equivalent age MRI findings in very preterm infants.
Sildenafil-Mediated Neuroprotection from Adult to Neonatal Brain Injury: Evidence, Mechanisms, and Future Translation.
Brain perfusion imaging in neonates.
Département de pédiatrie