
Indrit Bègue
Nom du groupe: Neuroimaging and translational psychiatry
Group type: Main
Affiliations: Department of Psychiatry
Domaines: Affective and Social Neurosciences
Mot clés: Apathy, Cognitive deficits, schizophrenia, transcranial magnetic stimulation, translational psychiatry
Activités de recherche
Our research focuses on the psychopathological, behavioral and neural processes underlying neuropsychiatric disorders (in particular, negative symptoms of schizophrenia) and their translational potential.
Our research work is organized in two axes:
- The first axis targets the neurobiological mechanisms of negative symptoms in schizophrenia by :
- combining advanced human functional and structural neuroimaging with clinical psychopathological measures
- aiming to identify reliable biomarkers in brain-wide association studies using large functional and structural datasets
- employing a translational cross-species examination approach
- The second axis aims at employing non-invasive therapeutic approaches including neuromodulation with transcranial magnetic stimulation and developing brief psychotherapeutic interventions for these extremely disabling symptoms for patients and their families.
Publications clés
A Longitudinal and Reproducible Anti-coactivation Pattern Between the Cerebellum and the Ventral Tegmental Area Relates to Apathy in Schizophrenia
Jade Awada*, Farnaz Delavari*, Thomas A.W. Bolton, Fares Alouf, Fabien Carruzzo, Noemie Kuenzi, Mariia Kaliuzhna, Tal Geffen, Teresa Katthagen, Florian Schlagenhauf, Dimitri Van De Ville, Stephan Eliez, Stefan Kaiser, Indrit Bègue
*Shared authorship
Biol Psychiatry, 2025 Jun 18:S0006-3223(25)01252-1
Cerebellar and cortico-striatal-midbrain contributions to reward-cognition processes and apathy within the psychosis continuum
Indrit Bègue, Yannis Elandaloussi, Farnaz Delavari, Hengyi Cao, Alexandra Moussa-Tooks, Mathilde Roser, Pierrick Coupé, Marion Leboyer, Stefan Kaiser, Josselin Houenou, Roscoe Brady, Charles Laidi
Cerebellum, 2024 Aug;23(4):1399-1410
Cerebellar and cortico-striatal-midbrain contributions to reward-cognition processes and apathy within the psychosis continuum
Indrit Bègue, Janis Brakowski, Erich Seifritz, Alain Dagher, Philippe N Tobler, Matthias Kirschner, Stefan Kaiser
Schizophr Res, 2022 Aug:246:85-94. doi: 10.1016/j.schres.2022.06.010