Frédéric Grouiller
Function: Adjoint scientifique
Nom du groupe: Innovative Clinical Multimodal Brain Imaging
Group type: Affiliated
Hosting group: Patrik Vuilleumier
Affiliations: Department of Basic Neurosciences
Domaines: Attention and Cognition
Mot clés: attention regulation, brain imaging, Magnetic resonance imaging, multimodal imaging, Neurofeedback, virtual reality
Activités de recherche
Our multidisciplinary research group is dedicated to advancing the field of multimodal imaging techniques for clinical applications. Our primary focus is to combine Magnetic Resonance Imaging (MRI) at 3 or 7T with other non-invasive tools to deepen our understanding of brain functions. By integrating these modalities, we strive to enhance the clinical workflow and improve the quality of life for patients. Our translational research is centered around three key areas:
– EEG/fMRI: development of novel tools to enable the integration of simultaneous EEG and fMRI, particularly in real-time applications such as bimodal neurofeedback. Our goal is to leverage this technology to help patients with attention deficits or epilepsy, facilitating targeted interventions and personalized treatment approaches.
– Virtual Reality (VR): combination of VR with MRI to explore alternative solutions to medication for children. Specifically, we seek to employ VR to assist children with attention deficit in regulating their attention and preparing them for MRI examinations without the need for anaesthesia.
– Quantitative functional brain mapping: development of new imaging techniques based on MRI perfusion to obtain quantitative mapping of functional brain functions. We aim to optimize patient outcomes by enhancing our ability to accurately delineate critical brain regions for surgical planning.
Publications clés
The relationship between EEG and fMRI connectomes is reproducible across simultaneous EEG-fMRI studies from 1.5T to 7T.
Modulation of epileptic networks by transient interictal epileptic activity: A dynamic approach to simultaneous EEG-fMRI.
Presurgical brain mapping in epilepsy using simultaneous EEG and functional MRI at ultra-high field: feasibility and first results.
Towards high-quality simultaneous EEG-fMRI at 7T: Detection and reduction of EEG artifacts due to head motion.
All-in-one interictal presurgical imaging in patients with epilepsy: single-session EEG/PET/(f)MRI.
Contact
Faculté de médecine
Université de Genève
Email: Frederic.Grouiller@unige.ch