Karl Schaller
Function: Professeur ordinaire
Nom du groupe: Geneva Neuro-glia-vascular Lab
Group type: Main
Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Clinical Neurosciences
Domaines: Development and Plasticity
Mot clés: brain injury, glia, neuroprotection, stroke
Activités de recherche
The main interest of our lab is to better understand the neuro-glia-vascular physiology in the normal and pathological brain. Our research focuses on the 3 most important cell types in the brain: neuron, astrocyte and endothelial cell. These cells are affected after stroke or brain trauma. Our aim is to investigate how these cells interacts using in vitro and in vivo models. This understanding is important for the development of new neuroprotective and restorative therapies. The group of Prof K. Schaller is comprised of three teams working on specific aspects of the neuro-glio-vascular unit. (Dr Bijlenga’s team, interested in intracellular calcium modifications in neurones and glia during ischemia ; Dr Badaut’s team, the role of the astrocyte in the brain water and energy homeostasis ; Dr da Silva’s team, the role of L-arginine/arginase pathway in the autocrine and paracrine regulation of the cell types present in the neuromuscular unit ; Dr Schatlo, investigating molecular mechanisms of brain damage following cerebral vasospasm following subarachnoid hemorrhage and stroke.)
Dernières publications
Electrophysiological Signatures of Alpha Coma.
Risk of Surgical Site Infection in Posterior Spine Surgery Using Different Closing Techniques: A Retrospective Study of Two Neurosurgical Centers.
Hypoalbuminemia in status epilepticus is a biomarker of short- and long-term mortality: A 9-year cohort study.
The Fork sign: a new cortical landmark in the human brain.
Videos
Contact
Département des neurosciences cliniques
HUG
Email: Karl.Schaller@hcuge.ch