Geneva University Neurocenter

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Nathalie Ginovart

Function: Professeure associée

Nom du groupe: Individual Differences and Vulnerability to Addiction

Group type: Main

Affiliations: Faculty of Medicine, Geneva University Hospitals, Department of Psychiatry

Domaines: Attention and Cognition

Mot clés: addictive behaviors, behavioral addiction

Department of Basic Neurosciences

Activités de recherche

Understanding how and why certain individuals have a greater propensity to develop addictive behaviors remains a major challenge in neuroscience. Our lab is interested in investigating the risk factors and underlying neural correlates conferring a predisposition to addictive disorders (drug and behavioral addictions) and related neuropsychiatric illnesses. More specifically, we focus on understanding the contribution and interplay of behavioral trait variables considered important in the psychopathologies of addictions – impulsivity, novelty seeking and risky-decision making – and neurochemical dysregulations of the mesocorticolimbic dopamine system to the development of addictive disorders. We use a cross-species translational approach combining behavioral testing with in vivo molecular imaging techniques in human and animal models, associated with pharmacological and genetic tools in rodents.

Dernières publications

Repeated Cocaine Intake Differentially Impacts Striatal D Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse.

Urueña-Méndez G , Dimiziani A , Bellés L , Goutaudier R , Ginovart N

International journal of molecular sciences - Aug 2023

Motor impulsivity but not risk-related impulsive choice is associated to drug intake and drug-primed relapse.

Arrondeau C , Urueña-Méndez G , Bellés L , Marchessaux F , Goutaudier R , Ginovart N

Frontiers in behavioral neuroscience - 2023

A cycle-consistent adversarial network for brain PET partial volume correction without prior anatomical information.

Sanaat A , Shooli H , Böhringer AS , Sadeghi M , Shiri I , Salimi Y , Ginovart N , Garibotto V , Arabi H , Zaidi H

European journal of nuclear medicine and molecular imaging - Jun 2023

Concurrent measures of impulsive action and choice are partially related and differentially modulated by dopamine D- and D-like receptors in a rat model of impulsivity.

Bellés L , Arrondeau C , Urueña-Méndez G , Ginovart N

Pharmacology, biochemistry, and behavior - Jan 2023

See the complete list of the publications

Hide the members of the Lab

Prof. Nathalie Ginovart

Group leader

CMU - E07.2550.B
+41 22 37 95 366
nathalie.ginovart@unige.ch

Chloe Arrondeau

Graduate student

CMU - E07.2550.A
+41 22 37 95 377
chloe.arrondeau@unige.ch

Florian Gilhet--Marchessaux

Graduate student

CMU - E07.2550.A
+41 22 37 95 377
florian.gilhet--marchessaux@unige.ch

Ginna Uruena Mendez

Graduate student

CMU - E07.2550.A
+41 22 37 95 377
ginna.uruenamendez@unige.ch

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Contact

Département de psychiatrie
Département des neurosciences fondamentales
HUG
Email: Nathalie.Ginovart@unige.ch